0818 Comorbid obstructive sleep apnea and insomnia in type 2 diabetes: Association with diabetes-related distress and glycemic control

Abstract Introduction It is unclear how comorbid insomnia and sleep duration may influence diabetes-related distress glycemic control in adults with obstructive apnea (OSA) type 2 diabetes (T2D). This analysis examined whether mediates the associations of OSA severity T2D based on duration. Methods study was a secondary merged baseline assessment data from two clinical trials (N=240) self-reported OSA. (apnea-hypopnea index ≥ 5) determined by home study. Participants completed questionnaires to elicit severity, distress, duration, daytime sleepiness, global quality. Sleep classified as normal (>6 h) or short (≤ 6h). Glycemic measured HbA1c (%). Mediation analyses bootstrapped samples were employed after controlling for sociodemographic covariates participants durations. Results More (mean age 57.8 years; 49.6% female; 65% White; 56.3% post high school education, mean 7.93%) had (n=128; 53.5%) than (n=111, 46.5%). significantly worse quality, insomnia, levels compared those (all p<.05). In associated (b=0.942, p=0.008); did not mediate association between (indirect effect [IE]=0.013, 95% CI: -0.003, 0.036). (b=1.470, p< 0.001), mediated (IE=0.023, 0.001, 0.053). Regardless HbA1c. Conclusion Only among contributes greater which leads higher levels. Short persons could be potential mechanism involved Support (if any) The NIH (R01- DK0960281; K24-NR016685) CTSI grants (UL1-RR024153; UL1-TR000005) funded parent studies